Electrical and mechanical activity of frog's heart in electrolyte-free solutions

Singh, Inderjit (1962) Electrical and mechanical activity of frog's heart in electrolyte-free solutions American Journal of Physiology- Legacy Content, 203 (3). pp. 422-424. ISSN 0002-9513

Full text not available from this repository.

Official URL: http://ajplegacy.physiology.org/content/203/3/422....

Abstract

Frog's heart continues to beat in half isotonic solution of sucrose, 0.112 m, for 2-3 hr. The mechanical activity in sucrose is accompanied by electrical activity. After the heart has adjusted to sucrose, sodium chloride produces a temporary inhibition before rhythmic beats are restored. The effect of epinephrine and norepinephrine is reversed; they produce inhibition instead of stimulation after the heart has become adapted to the sucrose solution. Acetylcholine produces inhibition. As an explanation of excitatory phenomena in electrolyte-free solutions, it is suggested that responses are due to activation of intracellular excitation and conduction mechanisms, and that the external ions only condition the membrane.

Item Type:Article
Source:Copyright of this article belongs to The American Physiological Society.
ID Code:52320
Deposited On:03 Aug 2011 06:18
Last Modified:03 Aug 2011 06:18

Repository Staff Only: item control page