Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea

Chaudhuri, P. K. ; Srivastava, Rashmi ; Kumar, Sunil ; Sushil Kumar, (2004) Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea Phytotherapy Research, 18 (2). pp. 114-117. ISSN 0951-418X

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ptr.127...

Related URL: http://dx.doi.org/10.1002/ptr.1278

Abstract

The phytochemicals betulinic acid (1), wogonin (2) and oroxindin (3) isolated from the aerial parts of Bacopa monnieri and Holmskioldia sanguinea showed significant antifungal activity against the two fungi Alternaria alternata and Fusarium fusiformis. Inhibition of root growth germination of wheat seeds was observed for all three compounds which showed 100% inhibition at 10 µg/mL. Compounds (1) and (2) showed potent inhibition of Alternaria alternata compared with oroxindin at a concentration of 4 µg/mL, whereas compound (2) was an effective inhibitor of both fungi. The structures of the compounds were established by spectral and chemical studies.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:Holmskioldia sanguinea; Verbenaceae; Bacopa monneiri; Scrophulariaceae
ID Code:52163
Deposited On:02 Aug 2011 07:56
Last Modified:02 Aug 2011 07:56

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