Synthetic approaches to homogynolides A and B

Srikrishna, A. ; Nagaraju, S. ; Reddy, T. J. ; Venkateswarlu, S. (1996) Synthetic approaches to homogynolides A and B Pure and Applied Chemistry, 68 (3). pp. 699-702. ISSN 0033-4545

Full text not available from this repository.

Official URL:

Related URL:


A four step, mcient and general methodology for the conversion of a cyclic ketone into the corresponding α-spiro-β-methylene-γ-butyrolactone, the key structural feature present in tricyclic sesquitepenes bakkanes, has been developed employing a regiospecific 5-exo̲ dig radical cyclisation reaction as the key step. The methodology has been extended to the total synthesis of bakkunes including homgynolide-B and chiral homogynolide-A.

Item Type:Article
Source:Copyright of this article belongs to International Union of Pure and Applied Chemistry.
ID Code:51581
Deposited On:28 Jul 2011 14:29
Last Modified:28 Jul 2011 14:29

Repository Staff Only: item control page