Light-induced modulation of self-assembly on spiropyran-capped gold nanoparticles: a potential system for the controlled release of amino acid derivatives

Ipe, Binil Itty ; Mahima, S. ; George Thomas, K. (2003) Light-induced modulation of self-assembly on spiropyran-capped gold nanoparticles: a potential system for the controlled release of amino acid derivatives Journal of the American Chemical Society, 125 (24). pp. 7174-7175. ISSN 0002-7863

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ja0341182

Related URL: http://dx.doi.org/10.1021/ja0341182

Abstract

A photoswitchable double-shell structure on Au nanoparticles, consisting of photochromic spiropyran as the first shell, which regulates the assembly and release of an outer shell of amino acid derivatives upon irradiation, is being reported for the first time. The light-regulated changes in the topographic properties of spiropyran-capped Au nanoparticles (i.e., interconversion between the zwitterionic and neutral forms) are exploited for the assembly and release of amino acid-based therapeutic agents such as L-DOPA.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:51399
Deposited On:28 Jul 2011 11:44
Last Modified:28 Jul 2011 11:44

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