Immune response in human subjects at high altitude

Chohan, I. S. ; Singh, I. ; Balakrishnan, K. ; Talwar, G. P. (1975) Immune response in human subjects at high altitude International Journal of Biometeorology, 19 (3). pp. 137-143. ISSN 0020-7128

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Official URL: http://www.springerlink.com/content/t532315w3k6x42...

Related URL: http://dx.doi.org/10.1007/BF01460012

Abstract

Levels of immunoglobulins were determined in persons exposed to high altitude. The individuals studied included high altitude natives, sea level residents at high altitude for 2 years, and recent arrivals at high altitude. Increased IgG and IgA levels were found in high altitude natives and sea level residents at high altitude for 2 years when compared with sea level residents. In recent arrivals marked increase of IgG and IgG levels and slight rise in IgM was seen. Recent arrivals who suffered from high altitude pulmonary oedema showed marked elevation of IgG, IgM, and IgA. Immunoglobulin responses to both primary and secondary TAB inoculation were of a higher magnitude and more sustained at high altitude than at sea level.

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ID Code:50684
Deposited On:26 Jul 2011 07:59
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