Differential affinity of anti-Pr-β-hCG-TT antibodies for hCG and hLH

Shastri, N. ; Dubey, S. K. ; Vijaya Raghavan, S. ; Salahuddin, M. ; Talwar, G. P. (1978) Differential affinity of anti-Pr-β-hCG-TT antibodies for hCG and hLH Contraception, 18 (1). pp. 23-24. ISSN 0010-7824

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Official URL: http://www.contraceptionjournal.org/article/0010-7...

Related URL: http://dx.doi.org/10.1016/0010-7824(78)90099-9

Abstract

Sera from four women immunized with the vaccine Pr-β-hCG-TT have been analysed for binding with hCG and hLH. Resolution of Scatchard plots showed the presence of more than one population of antibodies in these sera. In each case the Association Constants (Ka) of a population of antibodies for binding with hCG were distinctly higher than those for hLH. Results indicate the likely presence in β-hCG of determinants and/or conformations immunologically unique to hCG besides common regions.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:50581
Deposited On:26 Jul 2011 08:05
Last Modified:26 Jul 2011 08:05

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