Krishnan, K. S. ; Balaram, P. (1977) Nuclear magnetic resonance studies of the enzymatic hydrolysis of acetylcholine: a critical comment Molecular Pharmacology, 13 (4). pp. 621-624. ISSN 0026-895X
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Abstract
Studies at 100 MHz of the hydrolysis of acetylcholine by brain membrane-bound acetylcholinesterase show that the N-methyl resonance acquires a doublet character as the hydrolysis proceeds. These results provide a simple explanation for the time-dependent NMR line broadening observed earlier for the interaction of acetylcholine with purified acetylcholinesterase.
| Item Type: | Article |
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| Source: | Copyright of this article belongs to American Society for Pharmacology and Experimental Therapeutics. |
| ID Code: | 5045 |
| Deposited On: | 18 Oct 2010 05:23 |
| Last Modified: | 16 May 2016 15:36 |
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