Facile acid catalyzed ring cleavage of N-acylated lactams

Dixit, Arun N. ; Tandel, Sagun K. ; Rajappa, Srinivasachari (1994) Facile acid catalyzed ring cleavage of N-acylated lactams Tetrahedron Letters, 35 (33). pp. 6133-6134. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/004040...

Related URL: http://dx.doi.org/10.1016/0040-4039(94)88096-4

Abstract

N-Alkoxycarbonyl and N-arylsulfonyl lactams (1a-e) were prepared and converted to the corresponding acyclic products (2a-h) by acid catalyzed cleavage of the lactam ring in good yields and excellent regioselectivity.

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Deposited On:23 Jul 2011 07:19
Last Modified:23 Jul 2011 07:19

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