Genetic code preferentially conserves long-range interactions among the amino acids

Sitaramam, V. (1989) Genetic code preferentially conserves long-range interactions among the amino acids FEBS Letters, 247 (1). pp. 46-50. ISSN 0014-5793

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0014-5793(89)81237-2

Abstract

The physical properties of amino acids were investigated in order to evaluate their possible relationship to the assignment of codons for amino acids in the genetic code. A comparison of the interconversion probability between amino acids and the distances between the amino acids for individual physical properties revealed a striking hierarchy among the physical properties. Surprisingly, it is the long-range/solvent interactions and not the short-range/stereochemical properties which are preferentially conserved in the genetic code.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Physical Properties; Frozen Accident; Stereochemical Hypothesis/fluctuation
ID Code:49814
Deposited On:21 Jul 2011 10:04
Last Modified:21 Jul 2011 10:04

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