Kondala Rao, A. V. S. ; Shaha, Chandrima (2001) Multiple glutathione S-transferase isoforms are present on male germ cell plasma membrane FEBS Letters, 507 (2). pp. 174-180. ISSN 0014-5793
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0014-5793(01)02958-1
Abstract
Phase II detoxification enzymes, the glutathione S-transferases (GSTs) of 24 kDa are known to be cytosolic enzymes. This study shows that multiple GST isoforms that are 24 kDa in size are present on the extracellular side of the plasma membrane of rat male germ cells. The GST activity of male germ cell plasma membranes is several folds higher than somatic cell plasma membrane GST activity. Isoform composition of the germ cell plasma membrane and the cytosolic pool differ, GSTM5 and GSTPi being absent on the plasma membranes. The molecular masses of the common isoforms are comparable between the two pools and both pools show GST and glutathione peroxidase activity.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Glutathione S-transferase; Plasma Membrane; Germ Cell |
| ID Code: | 49608 |
| Deposited On: | 20 Jul 2011 14:15 |
| Last Modified: | 20 Jul 2011 14:15 |
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