Rajagopalan, Malini ; Ayyer, Jayalekshmy ; Sasisekharan, V. (1985) Interaction of non-intercalative drugs with DNA: distamycin analogues Journal of Biosciences, 7 (1). pp. 27-32. ISSN 0250-5991
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Official URL: http://www.ias.ac.in/jarch/jbiosci/7/27-32.pdf
Related URL: http://dx.doi.org/10.1007/BF02716763
Abstract
Distamycin and netropsin are two oligopeptides which bind to DNA in a nonintercalative manner. Analogues of distamycin have been synthesized and their binding with poly d(A-T) studied using ultraviolet absorption spectroscopy. Preliminary biological activity tests on a gram positive bacteria using these analogues have also been carried out.
| Item Type: | Article |
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| Source: | Copyright of this article belongs to Indian Academy of Sciences. |
| Keywords: | Non-intercalative Binding; DNA; Distamycin Analogues |
| ID Code: | 49595 |
| Deposited On: | 20 Jul 2011 14:24 |
| Last Modified: | 18 May 2016 04:15 |
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