Polymorphism in B-DNA: X-ray diffraction studies on Li-DNA fibres

Parrack, P. ; Sundaramoorthy, M. ; Sasisekharan, V. (1985) Polymorphism in B-DNA: X-ray diffraction studies on Li-DNA fibres Journal of Biosciences, 8 (3-4). pp. 507-516. ISSN 0250-5991

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Official URL: http://www.ias.ac.in/jarch/jbiosci/8/507-516.pdf

Related URL: http://dx.doi.org/10.1007/BF02702751


From X-ray diffraction studies it is generally believed that B-DNA has the structural parameters n=10 and h=3.4 Å. However, for the first time we report that polymorphism in the B-form can be observed in DNA fibres. This was achieved by the precise control of salt and humidity in fibres and by the application of the precession method of X-ray diffraction to DNA fibres. The significant result obtained is that n=10 is not observed for crystalline fibre patterns. In fact, n=10 and h=3.4 Å are not found to occur simultaneously. Instead, a range of values, n=9.6-10.0 and h=3.35 Å-3.41 Å is observed.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:Polymorphism; B-DNA; Fibre Diffraction
ID Code:49594
Deposited On:20 Jul 2011 14:24
Last Modified:18 May 2016 04:15

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