An analysis of side-chain conformation in proteins

Bhat, T. N. ; Sasisekharan, V. ; Vijayan, M. (1979) An analysis of side-chain conformation in proteins International Journal of Peptide & Protein Research, 13 (2). pp. 170-184. ISSN 0367-8377

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The crystal structures of a number of globular proteins are currently available. An analysis of the distribution of side-chains among different allowed conformations in these proteins has been carried out. The observed conformations of individual residues are discussed on the basis of well-known stereochemical criteria. The population distribution of side-chains in different allowed regions in conformational space can be explained largely on the basis of simple steric considerations. In addition to examining the conformational behaviour of individual residues, some population distributions of conformational angles of general interest involving groups of residues have also been analyzed.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:Amino Acid Residues; Conformational Angles; Globular Proteins; Population Distributions in Conformational Space; Side-chain Conformation
ID Code:49529
Deposited On:20 Jul 2011 14:23
Last Modified:15 Jul 2012 17:55

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