Synthesis of leader RNA and editing of P mRNA during transcription by rinderpest virus

Ghosh, Arundhati ; Nayak, R. ; Shaila, M. S. (1996) Synthesis of leader RNA and editing of P mRNA during transcription by rinderpest virus Virus Research, 41 (1). pp. 69-76. ISSN 0168-1702

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0168-1702(95)01276-1

Abstract

Purified rinderpest virus was earlier shown to transcribe in vitro, all virus-specific mRNAs with the promoter-proximal N mRNA being the most abundant. Presently, this transcription system has been shown to synthesize full length monocistronic mRNAs comparable to those made in infected cells. Small quantities of bi- and tricistronic mRNAs are also synthesized. Rinderpest virus synthesizes in vitro, a leader RNA of ~55 nucleotides in length. Purified rinderpest virus also exhibits RNA editing activity during the synthesis of P mRNA as shown by primer extension analysis of the mRNA products.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Rinderpest Virus; In Vitro Transcription; Leader RNA; RNA Editing
ID Code:49298
Deposited On:19 Jul 2011 13:59
Last Modified:19 Jul 2011 13:59

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