Ranganathan, Subramania ; Jayaraman, Narayanaswamy (1992) A general and versatile route to "Zinc finger" templates Tetrahedron Letters, 33 (44). pp. 6681-6682. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/S0040-4039(00)61018-3
Abstract
The basic zinc finger template is formed in a single step from PNHCys[ S-CH,2NHAc ] HisOMe and zinc chloride by a tandem complexation deprotection sequence. Template (1̲ ) is formed, in a single step, with an overall yield of 10% from l-cysteine, from PNHCys [ SCH2NHAc ] HisOMe[ P=Z, E=COOMe ] and ZnCl2 by a tandem complexation deprotection sequence.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 48875 |
| Deposited On: | 20 Jul 2011 06:41 |
| Last Modified: | 15 Jul 2012 10:07 |
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