The first total synthesis of the antimicrobial sesquiterpenes (±)-enokipodins A and B

Srikrishna, A. ; Srinivasa Rao, M. (2004) The first total synthesis of the antimicrobial sesquiterpenes (±)-enokipodins A and B Synlett (2). 0374-0376. ISSN 0936-5214

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-2003-45003

Abstract

Efficient first total synthesis of antimicrobial sesquiterpenes enokipodins A and B (1 and 2, respectively) and formal total synthesis of cuparene-1,4-diol (5) and cuparene-1,4-quinone (7) have been accomplished starting from 2,5-dimethoxy-4-methyl-acetophenone employing Claisen rearrangement and ring-closing metathesis reaction as key steps.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Sesquiterpenes; Enokipodins A and B; Ring-closing Metathesis; Claisen Rearrangement
ID Code:48809
Deposited On:15 Jul 2011 12:30
Last Modified:15 Jul 2011 12:30

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