An efficient ring-closing metathesis reaction of geminally disubstituted olefins using first generation Grubbs' catalyst: enantiospecific synthesis of pacifigorgianes

Srikrishna, A. ; Dethe, Dattatraya H. (2003) An efficient ring-closing metathesis reaction of geminally disubstituted olefins using first generation Grubbs' catalyst: enantiospecific synthesis of pacifigorgianes Tetrahedron Letters, 44 (42). pp. 7817-7820. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2003.08.076

Abstract

An efficient ring closing metathesis reaction with first generation Grubbs' catalyst [PhCH=RuCl2(PCy3)2] involving geminally disubstituted olefins has been discovered. It has been extended to the enantiospecific synthesis of pacifigorgiane sesquiterpenes.

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Deposited On:15 Jul 2011 12:30
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