Biswas, Sukla ; Sharma, Yagya D. (1994) Enhanced expression of Plasmodium falciparum heat shock protein PFHSP70-I at higher temperatures and parasite survival FEMS Microbiology Letters, 124 (3). pp. 425-429. ISSN 0378-1097
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Abstract
The effect of various body temperatures, encountered during malaria fever, on the synthesis of Plasmodium falciparum heat-shock protein called PFHSP70-I and parasite growth rates among five different isolates are described. The results show that after the exposure of parasites at 39°C for 30 min the amount of PFHSP70-I in all five isolates increased markedly and significantly, whereas parasite growth rates and the amount of total blood stage antigens remained almost unaffected. This indicates that the PFHSP70-I gene responds to heat-shock by producing higher amounts of PFHSP70-I protein, presumably to protect the parasite from being killed during malaria fever.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | Human Malaria; Parasite Isolates; Fever; Plasmodium falciparum |
| ID Code: | 48649 |
| Deposited On: | 15 Jul 2011 07:54 |
| Last Modified: | 15 Jul 2011 07:54 |
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