New hopes from endophytic fungal secondary metabolites

Tejesvi, M. V. ; Nalini, M. S. ; Mahesh, B. ; Prakash, H. S. ; Kini, K. R. ; Shetty, H. S. ; Subbiah, Ven (2007) New hopes from endophytic fungal secondary metabolites Boletín de la Sociedad Química de México, 1 (1). pp. 19-26. ISSN 1870-1809

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Official URL: http://www.bsqm.org.mx/PDFS/V1/N1/02-New%20hopes.p...

Abstract

The search for and exploitation of natural products and their properties has been the mainstay of biotechnology research. Natural product search and discovery from endophytes of medicinal plants represents a challenge to the biotechnologist. All the available evidence points to natural product discovery continuing strongly and accelerating as a consequence of new search strategies and innovative microbiology. In drug discovery, novel natural product chemotypes with interesting structures and biological activities continue to be reported. Without such discoveries, there would be a significant therapeutic deficit in several important clinical areas. The diverse range of biosynthetic pathways in plants, fungi and bacteria has provided an array of lead structures that have been used in drug development. This review highlights the importance of endophytes with desirable bioactivity, in a novel natural products screening programme.

Item Type:Article
Source:Copyright of this article belongs to The Mexican Chemical Society.
Keywords:Fungi; Bacteria; Yeasts; Endophytes; Natural Products
ID Code:48613
Deposited On:14 Jul 2011 14:07
Last Modified:14 Jul 2011 14:07

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