Monoclonal antibodies to synaptic macromolecules of Drosophila melanogaster

Rane, Nanda ; Jithra, Lopa ; Pinto, Ludwin ; Rodrigues, Veronica ; Krishnan, K. S. (1987) Monoclonal antibodies to synaptic macromolecules of Drosophila melanogaster Journal of Neuroimmunology, 16 (3). pp. 331-344. ISSN 0165-5728

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0165-5728(87)90109-3

Abstract

We have obtained monoclonal antibodies to Drosophila acetylcholinesterase, glutamate dehydrogenase as well as other unknown macromolecules which may have some relevance in synaptic function. The majority of antibodies against acetylcholinesterase recognised common epitopes on all four subunits- but one (MA2) was specific to a 110 kDa dimer. Antibodies to unknown synaptic macromolecules were identified by their selective staining in immunofluorescence studies. F2A3 stains sensory neurons and their synapses in the visual and olfactory systems.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Monoclonal Antibody; Synaptic Macromolecule; (Drosophila melanogaster)
ID Code:48368
Deposited On:14 Jul 2011 06:35
Last Modified:14 Jul 2011 06:35

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