Effect of defects on thermal denaturation of DNA oligomers

Singh, Navin ; Singh, Yashwant (2001) Effect of defects on thermal denaturation of DNA oligomers Physical Review E - Statistical, Nonlinear and Soft Matter Physics, 64 (4). 042901_1-042901_4. ISSN 1539-3755

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Official URL: http://pre.aps.org/abstract/PRE/v64/i4/e042901

Related URL: http://dx.doi.org/10.1103/PhysRevE.64.042901

Abstract

Effect of defects on the melting profile of short heterogeneous DNA chains is calculated using the Peyrard-Bishop Hamiltonian. On-site potential on a defect site is represented by a potential that has only a short-range repulsion and a flat part without well of the Morse potential. Stacking energy between two neigbouring pairs involving a defect site is also modified. The results are found to be in good agreement with the experiments.

Item Type:Article
Source:Copyright of this article belongs to American Physical Society.
ID Code:47969
Deposited On:12 Jul 2011 12:03
Last Modified:12 Jul 2011 12:03

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