One-pot synthesis of coumarins. Catalysis by the solid base, calcined Mg-Al hydrotalcite

Ramani, A. ; Chanda, B. M. ; Velu, S. ; Sivasanker, S. (1999) One-pot synthesis of coumarins. Catalysis by the solid base, calcined Mg-Al hydrotalcite Green Chemistry, 1 (3). pp. 163-165. ISSN 1463-9262

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Official URL: http://pubs.rsc.org/en/content/articlelanding/1999...

Related URL: http://dx.doi.org/10.1039/A903173A

Abstract

The synthesis of coumarins (2H-benzopyran-2-ones) via Knoevenagel condensation over a recoverable, inexpensive solid base catalyst, calcined Mg-Al hydrotalcite, is reported for the first time. This method produces substituted coumarins in very high yields (>85%) and selectivities (ca. 100%) when aromatic hydroxy aldehydes are reacted with 2-substituted ethyl acetate.

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