Thangaraj, Kumarasamy ; Ramana, Gutala V. ; Singh, Lalji (1999) Y-chromosome and mitochondrial DNA polymorphisms in Indian populations Electrophoresis, 20 (8). pp. 1743-1747. ISSN 0173-0835
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1...
Related URL: http://dx.doi.org/10.1002/(SICI)1522-2683(19990101)20:8<1743::AID-ELPS1743>3.0.CO;2-V
Abstract
Y-chromosome polymorphism using short tandem repeat (STR) markers on 94 normal males belonging to the Brahmin and Kamma caste populations of Andhra Pradesh, India, and Siddis, a migrant population from Africa, inhabiting Hyderabad, India, revealed heterogeneity as indicated by network analysis. We have observed population-specific haplotypes and alleles. Analysis of Y-Alu polymorphism (YAP) in Siddis showed the presence of Alu insertion in 40% of the individuals. However, YAP insertion was not found in Brahmins and Kammas. The dendrogram based on hypervariable region I (HVR I) of the displacement loop (D-loop) sequence of mitochondrial DNA (mtDNA) of Siddis showed genetic relationships to African populations. YAP and mtDNA analysis of Siddis also confirmed their immigration from Africa.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | Y-chromosome; Populations; Short Tandem Repeat; Y-Alu Polymorphism; Mitochondrial DNA |
| ID Code: | 46801 |
| Deposited On: | 06 Jul 2011 06:38 |
| Last Modified: | 06 Jul 2011 06:38 |
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