Restriction fragment polymorphism in the sex-determining region of the Y chromosomal DNA of European wild mice

Singh, L. ; Winking, H. ; Jones, K. W. ; Gropp, A. (1988) Restriction fragment polymorphism in the sex-determining region of the Y chromosomal DNA of European wild mice Molecular and General Genetics MGG, 212 (3). pp. 440-449. ISSN 0026-8925

Full text not available from this repository.

Official URL: http://www.springerlink.com/content/p054846l621647...

Related URL: http://dx.doi.org/10.1007/BF00330848

Abstract

Using 32P-labeled probe consisting mainly of (GATA)n we have shown that a male specific Alu1 DNA blot pattern which defines the Y chromosome sex-determining locus in inbred mice is highly polymorphic in wild mice, indicating substantial sequence evolution in this region under field conditions. In all cases examined by in situ hybridization, the region concerned is paracentromeric. In contrast, the blot pattern of another probe (M 34) which detects repeated sequences specific to the mouse Y chromosome but outside the sex-determining locus, remains constant between different isolates.

Item Type:Article
Source:Copyright of this article belongs to Springer.
Keywords:Bkm DNA; Polymorphism; Wild Mouse; Y Chromosome
ID Code:46788
Deposited On:06 Jul 2011 05:02
Last Modified:06 Jul 2011 05:02

Repository Staff Only: item control page