Valecha, Neena ; Sharma, V. P. ; Usha Devi, C. (1998) A rapid immunochromatographic test (ICT) for diagnosis of Plasmodium falciparum Diagnostic Microbiology and Infectious Disease, 30 (4). pp. 257-260. ISSN 0732-8893
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0732-8893(98)00003-0
Abstract
A field study was conducted to assess the sensitivity and specificity of rapid immunodiagnostic test based on detection of Plasmodium falciparum histidine-rich protein-2 (PfHRP-2) in peripheral blood for diagnosis of P. falciparum infection. Evaluation in 173 patients showed that the assay was 98.59% sensitive and 97.1% specific. There was no cross-reactivity with P. vivax. The test was positive in few patients who were found to be negative by microscopy showing the presence of antigen after curative chemotherapy. The test is a valuable diagnostic tool for falciparum malaria, especially in emergency/field situations requiring rapid diagnosis.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 46590 |
| Deposited On: | 05 Jul 2011 11:44 |
| Last Modified: | 05 Jul 2011 11:44 |
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