Malaria diagnosis by field workers using an immunochromatographic test

Singh, Neeru ; Valecha, Neena ; Sharma, V. P. (1997) Malaria diagnosis by field workers using an immunochromatographic test Transactions of the Royal Society of Tropical Medicine & Hygiene, 91 (4). pp. 396-397. ISSN 0035-9203

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A rapid immunodiagnostic test (ICT Malaria PfTestTM) has been developed by ICT Diagnostics (Sydney, Australia) for the diagnosis of Plasmodium falciparum infection. The test is an antigen capture assay based on the detection of P. falciparum histidine-rich protein 2 in peripheral blood. This study was undertaken to assess the performance and usefulness of the test as a diagnostic method in highly malarious, inaccessible forested villages of Mandla district, central India. In all, 353 patients with fever were scanned by the test in parallel with thick blood film examination. The sensitivity and specificity were 100% and 84·5%, respectively. The whole test took about 5 min. The test results became negative in most cases (70%) within 7 d after initiation of curative chemotherapy. The test is simple, easy to learn and accurate, and may prove to be an important tool in the battle against falciparum malaria.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Malaria; Plasmodium falciparum; Diagnosis; Rapid Antigen Capture Assay; ICT Malaria PfTest; Histidine-rich Protein 2
ID Code:46588
Deposited On:05 Jul 2011 11:42
Last Modified:05 Jul 2011 11:42

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