Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

Sasidharan, Abhilash ; Panchakarla, L. S. ; Chandran, Parwathy ; Menon, Deepthy ; Nair, Shantikumar ; Rao, C. N. R. ; Koyakutty, Manzoor (2011) Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene Nanoscale (3). pp. 2461-2464. ISSN 2040-3364

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Official URL: http://pubs.rsc.org/en/content/articlelanding/2011...

Related URL: http://dx.doi.org/10.1039/C1NR10172B

Abstract

We report the effect of carboxyl functionalization of graphene in pacifying its strong hydrophobic interaction with cells and associated toxic effects. Pristine graphene was found to accumulate on the cell membrane causing high oxidative stress leading to apoptosis, whereas carboxyl functionalized hydrophilic graphene was internalized by the cells without causing any toxicity.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:44585
Deposited On:22 Jun 2011 12:08
Last Modified:23 Jun 2012 08:35

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