Polypeptide models of collagen. Solution properties of (Gly-Pro-Sar)n and (Gly-Sar-Pro)n

Ananthanarayanan, V. S. ; Brahmachari, Samir K. ; Rapaka, Rao S. ; Bhatnagar, Rajendra S. (1976) Polypeptide models of collagen. Solution properties of (Gly-Pro-Sar)n and (Gly-Sar-Pro)n Biopolymers, 15 (4). pp. 707-716. ISSN 0006-3525

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/bip.197...

Related URL: http://dx.doi.org/10.1002/bip.1976.360150409

Abstract

Our studies on the solution conformation of (Gly-Pro-Sar)n and (Gly-Sar-Pro)n synthesized as polypeptide models for collagen are reported. It is found that, while (Gly-Pro-Sar)n exists in ordered triple-helical conformation, (Gly-Sar-Pro)n remains as a disordered random coil in water. Addition of certain helix-promoting solvents seems to generate order in (Gly-Sar-Pro)n.

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