Odor representations in the mammalian olfactory bulb

Khan, Adil Ghani ; Parthasarathy, K. ; Bhalla, Upinder Singh (2010) Odor representations in the mammalian olfactory bulb Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2 (5). pp. 603-611. ISSN 1939-5094

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Official URL: http://www3.interscience.wiley.com/journal/1233343...

Related URL: http://dx.doi.org/10.1002/wsbm.85

Abstract

A first key step in studying a sensory modality is to define how the brain represents the features of the sensory stimulus. This has proven to be a challenge in olfaction, where even the stimulus features have been a matter of considerable debate. In this review, we focus on olfactory representations in the first stage of the olfactory pathway, the olfactory bulb (OB). We examine the diverging viewpoints on spatially organized versus distributed representations. We then consider how odor sampling through respiration is a key part of the odorant code. Finally, we ask how the bulb handles the challenging task of representing mixtures. We suggest that current evidence points toward a representation that is spatially organized at the inputs but later distributed, with the spatial organization not being used for much computation. Nevertheless, this is a simple representation that effectively represents multiple individual odorants, as well as odor mixtures.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons, Inc.
ID Code:4382
Deposited On:13 Oct 2010 17:08
Last Modified:18 Jan 2011 09:52

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