Effect of deprivation of vitamin A on the basic proteins of the nuclei of rat testes

Rao, M. R. S. ; Singh, Jagmohan ; Ganguly, J. (1980) Effect of deprivation of vitamin A on the basic proteins of the nuclei of rat testes Biochemical and Biophysical Research Communications, 94 (1). pp. 1-8. ISSN 0006-291X

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00062...

Related URL: http://dx.doi.org/10.1016/S0006-291X(80)80178-1

Abstract

The relative concentrations of the major histones, namely, H1, TH1, H2A, H2B, H3 and H4 are not significantly changed in the testes of the vitamin A-deficient rats, as compared to those in the normal controls. But the testis-specific protein, TP, which is synthesized at the mid-spermatid stage, is markedly reduced in the testes of the deficient rats. On supplementation of the deficient rats with retinyl acetate for 28 days, there was a 50% recovery in the relative concentration of the TP with respect to the total amounts of H1 and TH1.

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