Ganesh, Subramaniam ; Raman, Rajiva (1997) CvSox-4, the lizard homologue of the human SOX4 gene, shows remarkable conservation among the amniotes Gene, 196 (1-2). pp. 287-290. ISSN 0378-1119
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S03781...
Related URL: http://dx.doi.org/10.1016/S0378-1119(97)00241-2
Abstract
SOX family genes share a high sequence similarity with the HMG box region of the human Y chromosomal gene, SRY. We have cloned and sequenced the HMG box motif of a Sox gene of the lizard, Calotes versicolor. A database search for the cloned sequence, CvSox-4, revealed 100% identity with the SOX4 gene of the human and its homologue in a bird. The result strongly suggests that SOX4 evolved prior to the diversification of amniotes and is highly conserved.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | SRY-related Gene; Reptiles; Evolution; HMG Box; Gene Cloning; Sex Determination |
| ID Code: | 41657 |
| Deposited On: | 30 May 2011 13:25 |
| Last Modified: | 30 May 2011 13:25 |
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