Ion exchange resin-mediated hydrolytic cleavage of epoxides. Simple one-pot synthesis of 2-arylketones from 1-aryl-1,2-epoxides

Ranu, Brindaban C. ; Chakraborty, Rupak (1990) Ion exchange resin-mediated hydrolytic cleavage of epoxides. Simple one-pot synthesis of 2-arylketones from 1-aryl-1,2-epoxides Synthetic Communications, 20 (12). pp. 1751-1756. ISSN 0039-7911

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Related URL: http://dx.doi.org/10.1080/00397919008053099

Abstract

Epoxides are cleaved in an aqueous solution with Dowex-50W. Alicyclic epoxides are converted to trans-1,2-diols whereas 1-aryl-1,2-epoxides furnish 2-arylketones in excellent yields.

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