Water-promoted highly regio- and stereoselective synthesis of α-dehydro-β-amino esters and nitriles from Baylis-Hillman acetates

Ghosh, Sudip ; Dey, Raju ; Chattopadhyay, Kalicharan ; Ranu, Brindaban C. (2009) Water-promoted highly regio- and stereoselective synthesis of α-dehydro-β-amino esters and nitriles from Baylis-Hillman acetates Tetrahedron Letters, 50 (34). pp. 4892-4895. ISSN 0040-4039

Full text not available from this repository.

Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2009.06.051

Abstract

The nucleophilic addition of amines to Baylis-Hillman acetates has been efficiently carried out in water at room temperature in the absence of any base, acid, or metal catalyst to produce α-dehydro-β-amino esters and nitriles. This procedure addresses a variety of aliphatic open-chain and cyclic amines and anilines. All the reactions are highly regio- and stereoselective, fast and high yielding.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Baylis–Hillman Adduct; α-dehydro-β-amino Esters; Water; Regioselectivity; Stereoselectivity
ID Code:41429
Deposited On:30 May 2011 05:34
Last Modified:30 May 2011 05:34

Repository Staff Only: item control page