Cyclic AMP production in isolated rat seminiferous tubule cell preparations: a potential in vitro assay for follicle stimulating hormone

Jagannadha Rao, A. ; Ramachandran, J. (1975) Cyclic AMP production in isolated rat seminiferous tubule cell preparations: a potential in vitro assay for follicle stimulating hormone Life Sciences, 17 (3). pp. 411-416. ISSN 0024-3205

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/002432...

Related URL: http://dx.doi.org/10.1016/0024-3205(75)90491-9

Abstract

A simple procedure for the isolation of rat seminiferous tubule cell preparations free of Leydig cells is described. Both ovine and human FSH stimulated cyclic AMP accumulation. in proportion to the concentration of the hormones. Other hormones, including ICSH and hCG, were inactive. It is proposed that stimulation of cyclic AMP accumulation in tubule cells may be a specific, sensitive and rapid in vitro assay for FSH.

Item Type:Article
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ID Code:40858
Deposited On:25 May 2011 09:15
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