A facile one-pot transformation of Baylis-Hillman adducts into unsymmetrical disubstituted maleimide and maleic anhydride frameworks: a facile synthesis of himanimide A

Basavaiah, Deevi ; Devendar, Badugu ; Aravindu, Kunche ; Veerendhar, Ainelly (2010) A facile one-pot transformation of Baylis-Hillman adducts into unsymmetrical disubstituted maleimide and maleic anhydride frameworks: a facile synthesis of himanimide A Chemistry - A European Journal, 16 (7). pp. 2031-2035. ISSN 0947-6539

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Official URL: http://www3.interscience.wiley.com/journal/1232481...

Related URL: http://dx.doi.org/10.1002/chem.200902887

Abstract

Unsymmetrical, disubstituted maleimide and maleic anhydride frameworks have been accessed from Baylis-Hillman adducts in an operationally simple three-step (Friedel-Crafts reaction, selective hydrolysis, and cyclization), one-pot strategy. This strategy has been successfully extended to the synthesis of a representative bioactive compound, himanimide A.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons, Inc.
Keywords:Friedel-crafts Reaction; Heterocycles; Himanimide A; Natural Products; Synthetic Methods
ID Code:3959
Deposited On:13 Oct 2010 07:09
Last Modified:17 Jan 2011 04:09

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