Epidemiology and molecular typing of Candida isolates from burn patients

Gupta, Nivedita ; Haque, Absarul ; Lattif, Ali Abdul ; Narayan, R. P. ; Mukhopadhyay, Gauranga ; Prasad, Rajendra (2004) Epidemiology and molecular typing of Candida isolates from burn patients Mycopathologia, 158 (4). pp. 397-405. ISSN 0301-486X

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Official URL: http://www.springerlink.com/content/w8106161x6j06k...

Related URL: http://dx.doi.org/10.1007/s11046-004-1820-x


This study, spread over a span of 2 years describes Candida infections in burn patients of an Indian hospital. A total of 220 burn patients were monitored and Candida could be isolated from 138 patients. A total of 228 different Candida species were obtained from various body locations of these patients. Species identification revealed that Candida albicans was the most predominant (45) followed by Candida tropicalis(33), Candida glabrata (13.5), C. parapsilosis (4), C. krusei (2.75) and C. kefyr (1.75). DNA fingerprinting of all C. albicans isolates was done by using CARE-2 probe. Fingerprinting analyses of all the C. albicans strains revealed that strains collected from different patients were different. It is noteworthy that patients with disseminated candidiasis had a similar, but unique strain isolated from all body locations, suggesting a possibility that commensal isolates might be turning pathogenic. Taken together, this is probably the first ever detailed survey of Candidainfections in burn patients in India and is expected to lead to better clinical management of this group of patients.

Item Type:Article
Source:Copyright of this article belongs to Springer.
Keywords:Burn; Candida albicans; CARE-2; Epidemiology; Fingerprinting; Immunocompromised
ID Code:39347
Deposited On:11 May 2011 13:03
Last Modified:11 May 2011 13:03

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