Roychoudhury, Arati ; Das, Tandra ; Sharma, Archana ; Talukder, Geeta (1993) Use of crude extract of garlic (Allium sativum L.) in reducing cytotoxic effects of arsenic in mouse bone marrow Phytotherapy Research, 7 (2). pp. 163-166. ISSN 0951-418X
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ptr.265...
Related URL: http://dx.doi.org/10.1002/ptr.2650070214
Abstract
A relatively high concentration of crude extract of garlic, (Allium sativum L.)-single clove variety, was found to reduce the cytotoxic effects of three doses of sodium arsenite, corresponding to 1/10, 1/30 and 1/50 of the LD50 in laboratory bred male Swiss albino mice. The animals were given a single oral dose of the chemical, together with the extract, and effects were observed after 24 h in bone marrow cells following the colchicine-fixation-airdry-Giemsa schedule. The endpoints scored were chromosomal aberrations and damaged cells.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | Crude Extract of Garlic; Sodium Arsenite Poisoning; Mice Bone Marrow Chromosomes |
| ID Code: | 39028 |
| Deposited On: | 06 May 2011 09:32 |
| Last Modified: | 06 May 2011 09:32 |
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