Giri, Ashok Kumar ; Talukder, Geeta ; Sharma, Archana (1986) Sister chromatid exchange induced by metanil yellow and nitrite singly and in combination in vivo on mice Cancer Letters, 31 (3). pp. 299-303. ISSN 0304-3835
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/030438...
Related URL: http://dx.doi.org/10.1016/0304-3835(86)90151-5
Abstract
In vivo sister chromatid exchanges (SCEs) induced by metanil yellow (a dye containing secondary amino group), sodium nitrite, and dye in combination with nitrite following treatment with acute doses were studied on mice. The incidence of SCEs was significantly high in both dye- and nitrite-treated series. However, a combination of half the concentrations of dye and nitrite, when used together, gave a frequency of SCE higher than that of either chemical, when given in full dose, indicating the stronger clastogenicity of the nitrosamine formed.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 38990 |
| Deposited On: | 05 May 2011 13:43 |
| Last Modified: | 05 May 2011 13:43 |
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