Agarwal, Kalpana ; Sharma, Archana ; Talukder, Geeta (1990) Clastogenic effects of copper sulphate on the bone marrow chromosomes of mice in vivo Mutation Research Letters, 243 (1). pp. 1-6. ISSN 0165-7992
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/016579...
Related URL: http://dx.doi.org/10.1016/0165-7992(90)90115-Z
Abstract
Copper sulphate administered intraperitoneally to Swiss albino mice in vivo induced a significant increase in the frequency of chromosomal aberrations in bone marrow cells at all concentrations used (1.1-6.6 mg/kg b.w.), when compared to the negative control. Statistical analysis indicates that the degree of clastogenicity was directly related to the concentrations used and indirectly to the period of exposure. The effect was maximal at 6 h after treatment as compared with 12 and 24 h.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Copper Sulphate, in Vivo; Bone Marrow Cells; Chromosome Aberrations |
| ID Code: | 38977 |
| Deposited On: | 05 May 2011 13:29 |
| Last Modified: | 05 May 2011 13:29 |
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