A new protocol for the syntheses of (E)-3-benzylidenechroman-4-ones: a simple synthesis of the methyl ether of bonducellin

Basavaiah, Deevi ; Bakthadoss, Manickam ; Pandiaraju, Subramanian (1998) A new protocol for the syntheses of (E)-3-benzylidenechroman-4-ones: a simple synthesis of the methyl ether of bonducellin Chemical Communications (16). pp. 1639-1640. ISSN 1359-7345

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Abstract

Development of a simple new methodology for the synthesis of (E)-3-benzylidenechroman-4-ones using methyl 3-aryl- 3-hydroxy-2-methylenepropanoates, the Baylis-Hillman adducts derived from methyl acrylate, and the application of this methodology for the synthesis of the methyl ether of bonducellin, an important natural product, and 3-(4-methoxybenzylidene)- 6-methoxychroman-4-one, an antifungal agent, are described.

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