Gupta, C. M. ; Puri, Anju ; Jain, Rakesh K. ; Bali, Anu ; Anand, Nitya (1986) Protection of mice against Plasmodium berghei infection by a tuftsin derivative FEBS Letters, 205 (2). pp. 351-354. ISSN 0014-5793
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001457...
Related URL: http://dx.doi.org/10.1016/0014-5793(86)80927-9
Abstract
In Plasmodium berghei infections, the mortality rate and parasitaemias were significantly reduced and the mean survival time was considerably enhanced by pretreating the animals with a tuftsin derivative, Thr-Lys-Pro-Arg-NH-(CH2)2-NHCOC15H31. This effect of the modified tuftsin was further increased upon its incorporation in the liposome bilayer. These results indicate that tuftsin and its derivatives may prove useful in enhancing nonspecific host resistance against protozoan infections.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Federation of European Biochemical Societies. |
| Keywords: | Protozoan Infection; Immunomodulation; Tuftsin; Liposome; Macrophage |
| ID Code: | 3893 |
| Deposited On: | 18 Oct 2010 09:29 |
| Last Modified: | 16 May 2016 14:36 |
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