A synthesis of 1,5-Di-O-acetyl-3-azido-2,3-dideoxy-D-ribofuranose

Gurjar, M. K. ; Pawar, S. M. ; Rama Rao, A. V. (1988) A synthesis of 1,5-Di-O-acetyl-3-azido-2,3-dideoxy-D-ribofuranose Journal of Carbohydrate Chemistry, 7 (1). pp. 271-275. ISSN 0732-8303

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Official URL: http://www.informaworld.com/index/762634570.pdf

Related URL: http://dx.doi.org/10.1080/07328308808058920


The renewed interest in azido-nucleosides, particularly when the aziodo group is present at position 3, has been intensified since the approval of 3'-azido-thymidine (1) for the treatment of AIDS. Moreover, 3'-amino-2,3-dideoxy-nucleosides are also important due to various biological activities associated with them. In dealing with the synthesis of such molecules, 3-azido-2,3-dideoxy-pentoses have been realised as valuable synthons.

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