The first synthesis of vancomycinic acid

Rama Rao, A. V. ; Laxma Reddy, K. ; Srinivasa Rao, A. (1994) The first synthesis of vancomycinic acid Tetrahedron Letters, 35 (28). pp. 5047-5050. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(00)73316-8

Abstract

Vancomycinic Acid moiety (C, D and E rings) 2 of vancomycin is synthesised making efficient use of the ease of nucleophilic displacements of halides on 2,6-dibromobenzoquinone followed by a diastereoselective elaboration of the quinone unit to aryl glycine.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Vancomycin; Vancomycinic Acid; Quinone Coupling; C-C Coupling; Asymmetric Dihydroxylation
ID Code:38836
Deposited On:05 May 2011 05:50
Last Modified:05 May 2011 05:50

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