Absorption of water and sodium and activity of adenosine triphosphatases in the rectal mucosa in tropical sprue

Ramakrishna, B. S. ; Mathan, V. I. (1989) Absorption of water and sodium and activity of adenosine triphosphatases in the rectal mucosa in tropical sprue Gut, 29 (5). pp. 665-668. ISSN 0017-5749

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Official URL: http://gut.bmj.com/content/29/5/665.abstract

Related URL: http://dx.doi.org/10.1136/gut.29.5.665

Abstract

In 10 southern Indian patients with tropical sprue, in vivo dialysis showed a defect of absorption of water and sodium from the rectum, when compared with 11 healthy volunteers. Sodium-potassium-ATPase activity, measured in homogenates of rectal biopsies, was significantly diminished in patients with sprue. Magnesium-ATPase and alkaline phosphatase were normal in biopsy homogenates. Decreased activity of colonic sodium-potassium-ATPase may contribute to diarrhoea in some patients with tropical sprue.

Item Type:Article
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