Cytochrome oxidase activity in rat retinal ganglion cells during postnatal development

Govindaiah, ; Shankaranarayana Rao, B. S. ; Ramamohan, Y. ; Singh, Y. K. ; Dhingra, Narender K. ; Raju, Trichur R. (2000) Cytochrome oxidase activity in rat retinal ganglion cells during postnatal development Developmental Brain Research, 124 (1-2). pp. 117-120. ISSN 0165-3806

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S01653...

Related URL: http://dx.doi.org/10.1016/S0165-3806(00)00092-4

Abstract

In this study, the metabolic activity of rat retinal ganglion cells during postnatal development has been examined in vivo using cytochrome oxidase histochemistry. The intensity of staining was measured by optical densitometry. The activity of cytochrome oxidase in retinal ganglion cells progressively increased from postnatal day 0 (P0) and reached a peak during the second week of postnatal development (P10-P14) and declined thereafter. Our data show that the increased levels of cytochrome oxidase seen in developing retinal ganglion cells occur at the same time, when neuronal maturity and synaptogenesis reach their peaks.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Retinal Ganglion Cell; Cytochrome Oxidase Histochemistry; Synaptogenesis; Postnatal Development; Optical Densitometry; Neuronal Maturity
ID Code:38514
Deposited On:23 May 2011 14:30
Last Modified:23 May 2011 14:30

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