Effect of chronic restraint stress on dendritic spines and excrescences of hippocampal CA3 pyramidal neurons - a quantitative study

Sunanda, ; Rao, Muddanna S. ; Raju, T. R. (1995) Effect of chronic restraint stress on dendritic spines and excrescences of hippocampal CA3 pyramidal neurons - a quantitative study Brain Research, 694 (1-2). pp. 312-317. ISSN 0006-8993

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000689...

Related URL: http://dx.doi.org/10.1016/0006-8993(95)00822-8

Abstract

Effect of chronic restraint stress on the number of dendritic spines and excrescences of hippocampal CA3 pyramidal neurons has been investigated. The results revealed a significant increase in the number of dendritic spines of apical and basal dendrites in rats subjected to restraint stress (6 h per day for 21 days). The number of excrescences were also markedly increased in stressed rats. The physiological significance and possible mechanism for increased spine density is discussed.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Chronic Restraint Stress; Dendritic Spine; Excrescence; Hippocampus
ID Code:38490
Deposited On:30 Apr 2011 08:48
Last Modified:30 Apr 2011 08:48

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