The responses of chemoreceptors at reduced temperatures

Paintal, A. S. (1971) The responses of chemoreceptors at reduced temperatures The Journal of Physiology, 217 (1). pp. 1-18. ISSN 0022-3751

PDF - Publisher Version

Official URL:


1. The responses of aortic chemoreceptors and pulmonary stretch receptors of cats were studied by recording impulses in individual fibres at normal body temperatures and thereafter at various temperatures down to 24-26° C while cooling the cat with ice. 2. Reduction of metabolism by lowering the temperature did not obviously slow the Po2 sensing mechanism of chemoreceptors but it greatly slowed the development of excitation after circulatory arrest. It also greatly reduced the excitatory effect of hypoxia. 3. The Q10 for the frequency of discharge of chemoreceptors (during maximal activity) was estimated by comparing the activity of the endings at normal body temperature after circulatory arrest (i.e. at a local Po2, of o mm Hg) with similar activity at reduced body temperatures. This averaged 2.5 in nine endings. The Q10 for the peak frequency of discharge also averaged 2.5 in seven endings. These values are similar to those of some mechano-receptors. 4. Apart from the reduction in the frequency of discharge (Q10 = 2.6) lowering the temperature did not alter the stimulus-response relationship of pulmonary stretch receptors. 5. The poor responses to ACh at lower temperatures indicate that ACh is not likely to be a transmitter at chemoreceptors.

Item Type:Article
Source:Copyright of this article belongs to Cambridge University Press.
ID Code:37881
Deposited On:23 Apr 2011 12:03
Last Modified:17 May 2016 20:47

Repository Staff Only: item control page