Addition of titanium ester enolates to aldimines containing a chiral α-methylbenzylamine moiety: synthesis of chiral syn-β-amino esters

Periasamy, Mariappan ; Suresh, Surisetti ; Selva Ganesana, Subramaniapillai (2006) Addition of titanium ester enolates to aldimines containing a chiral α-methylbenzylamine moiety: synthesis of chiral syn-β-amino esters Tetrahedron: Asymmetry, 17 (9). 1323-1331 . ISSN 0957-4166

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S09574...

Related URL: http://dx.doi.org/10.1016/j.tetasy.2006.04.032

Abstract

Addition of titanium ester enolates to N-arylidene derivatives containing a (R)-α-methylbenzylamine moiety afforded (2S,3S,αR)-β-amino esters in 73–93% yields with 86:14 to 96:4 diastereomeric ratios.

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Last Modified:25 Apr 2011 08:08

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