Resolution of trans-(±)-2-(pyrrolidinyl)cyclohexanol and its methyl ether using boric acid and chiral 1,1'-bi-2-naphthol

Periasamy, Mariappan ; Ramaraj Ramanathan, C. ; Sampath Kumar, Nangunoori (1999) Resolution of trans-(±)-2-(pyrrolidinyl)cyclohexanol and its methyl ether using boric acid and chiral 1,1'-bi-2-naphthol Tetrahedron: Asymmetry, 10 (12). 2307-2310 . ISSN 0957-4166

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S09574...

Related URL: http://dx.doi.org/10.1016/S0957-4166(99)00218-9

Abstract

The trans-(±)-2-(pyrrolidinyl)cyclohexanol 1, and its methyl ether 2 were resolved using chiral 1,1'-bi-2-naphthol and boric acid in THF or CH3CN. X-Ray structural analysis was carried out for the diastereomeric complex 3 obtained using 2.

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Deposited On:25 Apr 2011 08:05
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