Resolution of C2-symmetric 9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboxylic acid and 2,3-diphenylsuccinic acid using (S)-proline

Ramaraj Ramanathan, C. ; Periasamy, Mariappan (1998) Resolution of C2-symmetric 9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboxylic acid and 2,3-diphenylsuccinic acid using (S)-proline Tetrahedron: Asymmetry, 9 (15). 2651-2656 . ISSN 0957-4166

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S09574...

Related URL: http://dx.doi.org/10.1016/S0957-4166(98)00274-2

Abstract

Racemic 9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboxylic acid is resolved to obtain the corresponding (S,S)-isomer in 96±2% ee and the (R,R)-isomer in 97±2% ee through complexation with (S)-proline in methanol. The racemic 2,3-diphenylsuccinic acid has been resolved to obtain the (S,S)-isomer in 93% ee using (S)-proline in methanol.

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